Crime down there is bad, but not that bad. The OP asked for opinions on where to run presumably because he hates gyms. The route I showed is a safe one even without a weapon. Since this is not a weapons debate and people have differing views you may not like them, and that's fine. I still recommend this route as I was never attacked going around it hundreds of times. Running would probably be even less of an issue for security than biking.
Turn the heat O-F-F!