Beatup ...
As about a 75% MD-11 Captain, I've been able to hold daytime Reserve (1330 - 0130L) for several years (so I don't fly very many nights). Everything is a trade-off. Being on Reserve means I make slightly less money and work an extra day or two a month. As a commuter I have to have a crashpad and a car.
So, there are ways to avoid night flying if that's what you are interested in (but like someone said, we are in the overnight freight business).
This is a pretty good gig, most people find a way to make it work ...
YMMV
Mark