I agree totally with the idea of not dealing with the "usual" crowd of people. I had been instructing part-time for 4 years and finally left my regular job to instruct full time about 5 months ago.
The nights at home are nice, but right now I work 6 days a week, and only see them for about 1.5 - 2 hrs a day. With an airline, sure the schedule will be different, but I only get 4 days off per month now. The way I see it, Job Satisfaction + More time at home than I get now = QOL.
I just flat-out love flying, and I don't want to hire on with a company that wears me down and makes me hate my job 3 years from now. My goal has always been to be able to make a living doing what I love to do (yes, I know what the first year wages are at a regional!)