What ever supposed savings could be made by flying without pilots would soon be lost by a downfall in cash flow due to the theoretical 83% of people who would choose not to fly on a pilotless plane...Also unlikely that much of the savings from having no pilots would result in a dramatically lower ticket price.
Might see single pilot airliners at some stage, the job might change a bit, but i wouldn't be too worried of a pilotless jet if i was in the shoes of a new pilot starting out today.
With all the talk by the techies that 50% of jobs or whatever the number will be replaced by robots in the next however many of years. It'd be more likely that pilots and airline staff would lose to jobs to airline revenue decreasing due to mass unemployment-no disposable income for holidays/airline tickets- layoffs at the airlines, which then comes around full circle with the question being asked- whats the point of automating most jobs anyway when people end up having less and eventually no money to spend?.