Originally Posted by
aajones5
My intended population is airline pilots flying all kinds of routes. Different people's susceptibility to fatigue is not something I had considered, but not something I need to include at the moment.
You're not remotely interested, so long as you confine yourself to scheduled routes.
Scheduled airlines have the least isssue with fatigue and the greatest protection, as well as multiple layers of circadian protection.
If you really want to know about "jet lag" and it's effects, look at those who still aren't protected by the regulation and who work through numerous time zones on each side of the clock; supplemental carriers who go long distances, work all hours, don't enjoy regulatory protections ensuring circadian adaption and who work longer and harder duty hours across more time zones than scheduled airlines.
That's where you'll get your hard look.
All the work has been done and the matter addressed in depth for scheduled operators. Only the supplementals were carved out of the regulation and face the significant challenge. They're also the only ones excluded from your question, which suggests you're not really interested in real answers, but only rehashing what's already very well known.