For takeoff, you would normally select Flaps 1, 2 or 3 . If you put the flap selector in the 1 position, it will give you 1+F (as shown on the EICAS).
The a/c will automatically retract the flaps at 210 KIAS if 1+F is selected.
1+F is only something done at takeoff, and it basically means slats at 18 degrees and flaps at 10 degrees. On approach/landing, placing the flaps selector in the 1 position gives you just the setting of 1 (slats at 18 degrees, flaps at 0 degrees)