Yes, in fact most CAE made simulators are modeled after an exact serial number aircraft that may still be flying. For instance our Beechjets simulators are modeled after serial number 249, which still operates for a lawfirm in Florida. It has the exact same equipment list as the real airplane down to every switch and dial. Everything from the pilots viewpoint looks exactly as it would in the airplane, and I'd imagine many of the components are precisely the same ones found in the real aircraft. However, a few probably have been modified in order to work in the simulated world versus the real world environment.
I don't have much a technical background in simulators, but I have over 500 hours of acting as a fill-in captain or co-pilot for Level-C & D training sessions.