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WhiskyWhisky 06-16-2020 08:36 AM

Chinese or US Vaccine?
 
https://www.fiercepharma.com/pharma-...already-giving

As of today, all 1,120 volunteers in the phase 1/2 trial have received two injections of the vaccine at low, middle or high dosing strengths—or placebo—either 14 days, 21 days or 28 days apart, according to CNBG. The seroconversion rate for the 14-day and 21-day schedule of the mid-dose was 97.6%. At 28 days, it was 100%.

Would you take a Chinese Vaccine? Or wait for a US Vaccine?

WhiskyWhisky 06-16-2020 08:40 AM

October One
 
Oct 1st - Let's Roll.

https://www.cnbc.com/2020/06/16/astr...-ceo-says.html

Excargodog 06-16-2020 08:50 AM


Originally Posted by WhiskyWhisky (Post 3076299)
https://www.fiercepharma.com/pharma-...already-giving

As of today, all 1,120 volunteers in the phase 1/2 trial have received two injections of the vaccine at low, middle or high dosing strengths—or placebo—either 14 days, 21 days or 28 days apart, according to CNBG. The seroconversion rate for the 14-day and 21-day schedule of the mid-dose was 97.6%. At 28 days, it was 100%.

Would you take a Chinese Vaccine? Or wait for a US Vaccine?

Are these the same guys who claimed there was no human to human spread?

or were all those guys killed off in the human to human spread ?

Gundriver64 06-18-2020 06:17 AM

Kind of cracks me up (in somewhat of a sad fashion), all those who firmly believe that a COVID 19 vaccine is going to be a silver bullet for control of this virion. We've had vaccines for decades for certain diseases and the efficacy is all over the map (flu, measles, etc., etc.) with respect to effectiveness.

rickair7777 06-18-2020 07:50 AM


Originally Posted by Gundriver64 (Post 3077297)
Kind of cracks me up (in somewhat of a sad fashion), all those who firmly believe that a COVID 19 vaccine is going to be a silver bullet for control of this virion. We've had vaccines for decades for certain diseases and the efficacy is all over the map (flu, measles, etc., etc.) with respect to effectiveness.

Flu is different, and much harder to vaccinate against. Apples to Oranges.

There are multiple strains of flu in circulation, and each year they incubate and mutate in a vicious loop of domestic pigs, chickens, and peasants in asia. Every year that loop has to be analyzed, and they have to guess which strains will most likely prevail in the fall. Then they select 3-4 of those strains for the flu shot, which is a cocktail of vaccines. If the scientists guess wrong, or you get exposed to a strain that's not in the shot, you can get sick. Although getting the shot each year for many years improves your odds... you're running around with at least some immunity to dozens of strains. I never get the flu anymore, probably because the mil insisted I get a flu shot every year since the '80s.

'Rona is less likely to mutate as much as flu, and has not developed into something which gets into livestock, or is transmitted from people to animals. It took the flu a very long time to evolve into what it is, and that happened before modern medicine. We're not going to end up with a perpetual reservoir of mutating covid in cattle, sheep, and cowboys in Montana.

A vaccine does not have to be perfect to establish herd immunity. Given the amount of money and effort being dedicated to a covid vaccine, I'm pretty confident we can get to herd immunity sooner rather than later. We've defeated/marginalized every other dangerous virus since the advent of vaccines, one way or another (HIV is a special case since it actually eats the immune cells which respond to it). The uncertainty would be if covid starts mutating rapidly, but even so viruses tend to become less severe as they mutate. Covid is already observed to be mutating very slowly. Worst case we might need a vaccine cocktail like with the flu.

What's the plan if we don't have a vaccine? Lockdown forever?

Gundriver64 06-18-2020 08:05 AM


Originally Posted by rickair7777 (Post 3077331)
Flu is different, and much harder to vaccinate against. Apples to Oranges.

There are multiple strains of flu in circulation, and each year they incubate in a vicious loop of domestic pigs, chickens, and peasants in asia. Every year that loop has to be analyzed, and they have to guess which strains will most likely prevail in the fall. Then they select 3-4 of those strains for the flu shot, which is a cocktail of vaccines. If the scientists guess wrong, or you get exposed to a strain that's not in the shot, you can get sick. Although getting the shot each year for many years improves your odds... you're running around with at least some immunity to dozens of strains. I never get the flu anymore, probably because the mil insisted I get a flu shot every year since the '80s.

'Rona is a biologically/genetically different type of virus which is less likely to mutate as much as flu, and has not developed into something which gets into livestock, or is transmitted from people to animals. It took the flu a very long time to evolve into what it is, and that happened before modern medicine. We're not going to end up with a perpetual reservoir of covid in cattle. sheep, and cowboys in Montana.

A vaccine does not have to be perfect to establish herd immunity.

I'll think I'll stick with my resource (privileged conduit of information) at the CDC and what they have to say about these vaccines as they relate to CV-19.

rickair7777 06-18-2020 08:17 AM


Originally Posted by Gundriver64 (Post 3077338)
I'll think I'll stick with my resource (privileged conduit of information) at the CDC and what they have to say about these vaccines as they relate to CV-19.

My cousin is PHS officer and CDC staffer. She's not particularly pessimistic. Private sector tends to be a little out ahead of government bureaucrats in normal times, I'd hazard that industry might be leaving the CDC in the dust on this right now. they're certainly putting their money where their mouth is... a lot of money.

No vaccine, we might be looking at 50% demand in Q3 2021, between COVID fear and broad economic fallout. I know for fact of at least two major airlines who have a plan C for 30% demand next year.

Excargodog 06-18-2020 08:58 AM


Originally Posted by rickair7777 (Post 3077343)
My cousin is PHS officer and CDC staffer. She's not particularly pessimistic. Private sector tends to be a little out ahead of government bureaucrats in normal times, I'd hazard that industry might be leaving the CDC in the dust on this right now. they're certainly putting their money where their mouth is... a lot of money.

No vaccine, we might be looking at 50% demand in Q3 2021, between COVID fear and broad economic fallout. I know for fact of at least two major airlines who have a plan C for 30% demand next year.


https://i.ibb.co/HYLXkmb/E3-A9342-D-...-A72-F1-E3.jpg

https://www.medicinenet.com/when_covid-19_mutates_what_are_the_risks-news.htm

Gundriver64 06-18-2020 10:24 AM


Originally Posted by rickair7777 (Post 3077343)
My cousin is PHS officer and CDC staffer. She's not particularly pessimistic. Private sector tends to be a little out ahead of government bureaucrats in normal times, I'd hazard that industry might be leaving the CDC in the dust on this right now. they're certainly putting their money where their mouth is... a lot of money.

No vaccine, we might be looking at 50% demand in Q3 2021, between COVID fear and broad economic fallout. I know for fact of at least two major airlines who have a plan C for 30% demand next year.

The CDC is working in tandem with academia/private sector with respect to CV-19. The "in the dust" rhetoric is a stretch. My CDC circle includes an infectious disease doc who's retired from the CDC and now works exclusively for the Gates Foundation on the virus. Her expectations more or less parallel colleagues at the CDC's Division of Viral Diseases.

rickair7777 06-18-2020 10:55 AM

Flu is worse in the real world than these numbers portray, because of it's asian breeding loop.


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