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Promising Treatment & Immunity

Old 05-15-2020, 06:54 AM
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Default Promising Treatment & Immunity

I was actually quite surprised to see Sorrento Theuraputics make these statements out of the blue today....

https://www.sandiegouniontribune.com...hting-covid-19

Looks simpler and quicker to validate and trial then a vaccine. If it works like they think it does, it would provide a quick OVID cure, plus it could be used to confer temporary immunity (weeks? months?) to healthy people to allow them to circulate freely in society.
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Old 05-15-2020, 07:33 AM
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Originally Posted by rickair7777 View Post
I was actually quite surprised to see Sorrento Theuraputics make these statements out of the blue today....

https://www.sandiegouniontribune.com...hting-covid-19

Looks simpler and quicker to validate and trial then a vaccine. If it works like they think it does, it would provide a quick OVID cure, plus it could be used to confer temporary immunity (weeks? months?) to healthy people to allow them to circulate freely in society.
Does look game changing, production at 200,000 per month initially. If approved this IP could be licensed and everyone who wants to be immune could be before the end of the year!

BTW their stock symbol is SRNE
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Old 05-15-2020, 07:47 AM
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Originally Posted by ReachHeavy View Post
Does look game changing, production at 200,000 per month initially. If approved this IP could be licensed and everyone who wants to be immune could be before the end of the year!

BTW their stock symbol is SRNE
Their stock is already through the roof. That's actually what gives me some confidence in this one, they are an established public company in bio-tech and if they misled investors with a half-baked PR stunt they'd be in a world of hurt. They must be pretty darn sure of themselves. Might call em up and see if they're hiring.
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Old 05-15-2020, 08:18 AM
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Don't get too excited. Other therapies have worked in the lab but then fail in animal or clinical trials. This still has away to go before it is of any use.
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Old 05-15-2020, 08:30 AM
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Originally Posted by rickair7777 View Post
I was actually quite surprised to see Sorrento Theuraputics make these statements out of the blue today....

https://www.sandiegouniontribune.com...hting-covid-19

Looks simpler and quicker to validate and trial then a vaccine. If it works like they think it does, it would provide a quick OVID cure, plus it could be used to confer temporary immunity (weeks? months?) to healthy people to allow them to circulate freely in society.

Suprising PR release.. i don't know this company at all. I see they bought a GMP contract manufacturing facility but I can't find any products that they have an approved NDA for? I see they have some planned INDs. Maybe I'm missing it somewhere.

Looks like it was a preclinical study, in vitro. Or was animal dosing done? I can't find anything from what I read with data. Maybe something more detailed out there.

A lot has changed in monoclonal antibodies, but they still take forever to develop. Computer modeling and Carc/Tox studies being done virtually reduce time quite a bit. You never know what an antibody does until gets into the human body though. Fingers crossed....
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Old 05-15-2020, 08:47 AM
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Originally Posted by TXWarEagle View Post
Don't get too excited. Other therapies have worked in the lab but then fail in animal or clinical trials. This still has away to go before it is of any use.
Exactly. There are many other similar antibody therapies that are in far more advanced stages of testing, such as the one by Distributed Bio.

As far as other types of therapies are concerned, one of the most promising out there is Leronlimab. It’s currently going through placebo-controlled trials at top university hospitals such as UCLA and we should start seeing some results in the upcoming weeks. It was originally designed as an HIV drug, but it has shown some excellent results treating COVID patients in preliminary testing.

https://www.nbclosangeles.com/news/c...speed/2345620/

https://clinicaltrials.gov/ct2/show/NCT04347239

Last edited by sigler; 05-15-2020 at 09:11 AM.
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Old 05-15-2020, 08:59 AM
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Originally Posted by rickair7777 View Post
Their stock is already through the roof. That's actually what gives me some confidence in this one, they are an established public company in bio-tech and if they misled investors with a half-baked PR stunt they'd be in a world of hurt. They must be pretty darn sure of themselves. Might call em up and see if they're hiring.
stock going higher means a lot of people are buying. nothing more. it will crash 150% if the non-human tested-yet study fails

todays companies use carefully worded press statements to remain clear of SEC's gunsites. to include a disclaimer at the end.

lots of legalese in the press release:

shows potential
expects
could potentially
will likely be
initial tests
strong canditate

Press release was issued by the company themselves, and shotgunned to all media outlets. Local San Diego paper picked up the story about the local San Diego company.

stock is up

https://investors.sorrentotherapeuti...node/11241/pdf
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Old 05-15-2020, 09:36 AM
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Originally Posted by senecacaptain View Post
stock going higher means a lot of people are buying. nothing more. it will crash 150% if the non-human tested-yet study fails

todays companies use carefully worded press statements to remain clear of SEC's gunsites. to include a disclaimer at the end.

lots of legalese in the press release:

shows potential
expects
could potentially
will likely be
initial tests
strong canditate

Press release was issued by the company themselves, and shotgunned to all media outlets. Local San Diego paper picked up the story about the local San Diego company.

stock is up

https://investors.sorrentotherapeuti...node/11241/pdf
Yes, there's an art to that game, but it was still a bold move... confident or risky, one of the two.

National media picked it up as well.
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Old 05-15-2020, 09:46 AM
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Originally Posted by rickair7777 View Post
Yes, there's an art to that game, but it was still a bold move... confident or risky, one of the two.

National media picked it up as well.
they sure did

https://seekingalpha.com/news/357516...ure-feuerstein
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Old 05-15-2020, 10:32 AM
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Originally Posted by senecacaptain View Post
They've been around a long time, decades. So they just decided to do a pump-n-dump now, and maybe go to federal prison in the process?

But like all things bio-tech, very cautious optimism is as far as you want to go, otherwise may as well go to vegas.
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