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Vaccine Development Summary

Old 07-21-2020, 07:41 PM
  #31  
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Originally Posted by furloughfuntime View Post
It all makes sense now.

lol

in other news, I found a new mission for ALPA to undertake to support pilots afflicted with Covid19

https://www.forbes.com/sites/emilyea.../#7537f5a14d9d

#pot4pilots
maybe that guy i knew in college was right that "a doobie a day keeps the doctor away"


They roll out the ganga as the miracle cure for just about anything. Greatest snake oil ever (since they took coca out of soda pop).

You don't even need a medical excuse to toke these days, it mostly legal now.
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Old 07-22-2020, 03:45 AM
  #32  
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Originally Posted by rickair7777 View Post
His problem is he's retired and his experience is 40 years out of date. But whether to get vaccinated is of course your choice.
Actually, my greatest concern right now is that my employer will bow to the mob again and require vaccination just as they required a mandatory Covid test recently.

A swab up the nose to mollify customers is one thing. Injecting an unproven and minimally tested substance into your body in something else entirely.
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Old 07-22-2020, 05:34 AM
  #33  
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Originally Posted by GeeWizDriver View Post
Actually, my greatest concern right now is that my employer will bow to the mob again and require vaccination just as they required a mandatory Covid test recently.

A swab up the nose to mollify customers is one thing. Injecting an unproven and minimally tested substance into your body in something else entirely.
I have said from the beginning it would not surprise me especially with the lack of control we have in the US for other countries to require it for a US passport holder to enter. So while your company may not require you might have to stay strictly domestic. (if possible.)
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Old 07-22-2020, 07:09 AM
  #34  
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Originally Posted by GeeWizDriver View Post
Actually, my greatest concern right now is that my employer will bow to the mob again and require vaccination just as they required a mandatory Covid test recently.

A swab up the nose to mollify customers is one thing. Injecting an unproven and minimally tested substance into your body in something else entirely.
Plan on it. You don't have to get a vaccine.

But businesses, organizations, schools, and employers don't have to let you in their facility either.

But right now they seem on track to complete all normal regulatory testing of any vaccine. They can shortcut financing, red tape, and manufacturing, but it does not appear that anyone has any appetite to deploy a vaccine before phase III trails are complete. That might have been different if the bug had a fatality rate of 30% and a billion people caught it.

Phase IV is done after deployment and consists of surveillance of end users, just in case anything pops up. So you could consider early users of any vaccine or pharma to be part of the evaluation process. I'm still willing to go to work, which carries some slight but non-zero risk, so personally I'm willing to take a new vaccine which will carry lower risk than covid.

Biology is complex, so a new vaccine *might possibly* have unexpected side effects... but there's no particular reason to think it will either. Your airplane might crash too, but if you had reason to suspect a problem you'd just go back to the gate.

Last edited by rickair7777; 07-22-2020 at 07:23 AM.
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Old 07-22-2020, 07:11 AM
  #35  
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Originally Posted by GeeWizDriver View Post
A retired pathologist of my acquaintance, one with 40 years of experience in virology and infectious disease, explained the vaccine development process to me at dinner last Tuesday night. In detail. Long story short, it's a year to develop in the lab. Then two years to verify safety. Then another two years to verify effectiveness. Five years total. On a fast track.

He and his wife are in their mid 70's and he said there is no way in HE// they will subject themselves to a vaccine developed in less than a year.
Hes also never seen a vaccine that modern medicine has wanted more badly than this one. Every major government is throwing billions for a vaccine.
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Old 07-22-2020, 07:13 AM
  #36  
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The Ebola vaccine has proven very effective.
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Old 07-22-2020, 07:23 AM
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Originally Posted by Meep View Post
Hes also never seen a vaccine that modern medicine has wanted more badly than this one. Every major government is throwing billions for a vaccine.
Are they throwing the billions at the time machine? It takes TIME to make sure a vaccine is SAFE and EFFECTIVE. DNA sequencing tech has certainly shortened the development of vaccines. But you have to WAIT for clinical trial results if you want to make sure there are no unintended consequences to the vaccine.
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Old 07-22-2020, 07:27 AM
  #38  
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Originally Posted by GeeWizDriver View Post
Are they throwing the billions at the time machine? It takes TIME to make sure a vaccine is SAFE and EFFECTIVE. DNA sequencing tech has certainly shortened the development of vaccines. But you have to WAIT for clinical trial results if you want to make sure there are no unintended consequences to the vaccine.
They are waiting. See my post above.
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Old 07-22-2020, 07:55 AM
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Originally Posted by GeeWizDriver View Post
Are they throwing the billions at the time machine? It takes TIME to make sure a vaccine is SAFE and EFFECTIVE. DNA sequencing tech has certainly shortened the development of vaccines. But you have to WAIT for clinical trial results if you want to make sure there are no unintended consequences to the vaccine.

I was gonna say so far only Russia and China have said f.... it and given authorization before phase 3.
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Old 07-22-2020, 08:00 AM
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Originally Posted by BoilerUP View Post
The Ebola vaccine has proven very effective.
???

For values of effective I guess.

https://www.scientificamerican.com/a...al-drc-region/


More than 80% of people who were vaccinated didn’t end up with the disease, said Muyembe, and those who did had relatively mild cases.

https://www.nature.com/articles/d41586-020-01950-0

But it was an epidemic that involved immunizing only 300,000 people, and even so it took two years. And another epidemic of Ebola has already broken out on the other side of the country. And - despite the problems they had with vaccine acceptance, people are a lot more willing to be vaccinated against something with a 50% mortality than they are against something with a 0.5% (or less for the young) mortality.

I’m not against immunizations and certainly hope that we come up with an effective, safe, and cheap vaccine. But I don’t think it will be the panacea everyone seems to assume it will be. Public acceptance and the sheer logistics of any mass immunization process are serious issues that will need to be overcome, even with a perfect vaccine.
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