Vaccine Development Summary
04-01-2021, 12:23 AM
#882
:-)
Joined APC: Feb 2007
Posts: 7,339
Dual-antigen viral vector to prevent variants.
https://www.biorxiv.org/content/10.1...476v1.full.pdf
https://www.biorxiv.org/content/10.1...476v1.full.pdf
04-01-2021, 05:40 AM
#883
Prime Minister/Moderator
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,211
Pfizer 91% effective to-date, in extended trials which include various variant strains (100%-ish effective against SA strain).
https://www.reuters.com/article/us-h...-idUSKBN2BO55Y
https://www.reuters.com/article/us-h...-idUSKBN2BO55Y
04-06-2021, 06:10 AM
#884
Prime Minister/Moderator
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,211
Valneva doing phase-3 trials, a little late to the party but this is the only Western vaccine using old-school inactivated virus technology.
https://www.reuters.com/article/us-h...-idUSKBN2BT0RL
https://www.reuters.com/article/us-h...-idUSKBN2BT0RL
04-06-2021, 01:06 PM
#885
Prime Minister/Moderator
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,211
European agency now says clear link between AZ vaccine and rare blood clot issues...
https://www.reuters.com/article/us-h...-idUSKBN2BT1ER
https://www.reuters.com/article/us-h...-idUSKBN2BT1ER
04-06-2021, 06:56 PM
#886
Clear ECAM
Joined APC: Oct 2014
Posts: 883
Looks like someone was speaking a bit out of turn.
https://www.theguardian.com/world/20...ne-blood-clots
“In my opinion, we can now say it, it is clear that there is an association (of the brain blood clots) with the vaccine. However, we still do not know what causes this reaction,” Marco Cavaleri, chair of the vaccine evaulation team at the EMA, told Italian daily Il Messagero.
Cavaleri provided no evidence to support his comment.
Cavaleri provided no evidence to support his comment.
Europe’s drug regulator has denied it has already established a causal connection between the Oxford/AstraZeneca vaccine and a rare blood clotting syndrome, after a senior official from the agency said there was a link.
In a statement to Agence France-Presse, the European Medicines Agency (EMA) said on Tuesday it had “not yet reached a conclusion and the review is currently ongoing”, adding that it expected to announce its findings on Wednesday or Thursday.
In a statement to Agence France-Presse, the European Medicines Agency (EMA) said on Tuesday it had “not yet reached a conclusion and the review is currently ongoing”, adding that it expected to announce its findings on Wednesday or Thursday.
04-07-2021, 11:16 AM
#887
Prime Minister/Moderator
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,211
Regulators think clotting issue is very rare, enough so that the AZ vaccine is safer than not getting vaccinated. UK recommends that this vaccine not be given to people under 30 if possible. AZ vaccine is important for the developing world, since it doesn't require the cold-chain of some other vaccines.
https://www.reuters.com/article/us-h...-idUSKBN2BU27C
https://www.reuters.com/article/us-h...-idUSKBN2BU27C
04-07-2021, 11:38 AM
#888
Perennial Reserve
Joined APC: Jan 2018
Posts: 11,480
Originally Posted by rickair7777
Regulators think clotting issue is very rare, enough so that the AZ vaccine is safer than not getting vaccinated. UK recommends that this vaccine not be given to people under 30 if possible. AZ vaccine is important for the developing world, since it doesn't require the cold-chain of some other vaccines.
https://www.reuters.com/article/us-h...-idUSKBN2BU27C
https://www.reuters.com/article/us-h...-idUSKBN2BU27C
It would be unusual indeed to find a pharmaceutical with NO risk. We use a lot of medications - especially some antibiotics and sulfa drugs - that have rare but very severe reactions. The key issue is for the reward to be greater than the risk. For the young right now that’s a more difficult call than it is for your average 60 year old.
04-11-2021, 07:00 AM
#889
Prime Minister/Moderator
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,211
China considering mixing vaccines to enhance efficacy. They have four indigenous vaccines, but their efficacy is a bit lower than some of the Western vaccines, especially for new variants...
https://www.reuters.com/article/us-h...-idUSKBN2BY0H1
https://www.reuters.com/article/us-h...-idUSKBN2BY0H1
04-11-2021, 07:31 AM
#890
Prime Minister/Moderator
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,211
Data analyses hints that pfizer vaccine is somewhat less effective against SA variant, exact numbers not available from the limited sample size...
https://www.aljazeera.com/news/2021/...ine-study-says
https://www.aljazeera.com/news/2021/...ine-study-says
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