mRNA Vaccines
#1
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Joined APC: Mar 2020
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mRNA Vaccines
Looks like the first to the street are going to be messenger RNA based, a relatively new type of vaccine. The tech makes sense. Any smart medical/biotech types in here have any input on the safety of these types of vaccines? Looks like efficacy seems to be there...?
#2
Looks like the first to the street are going to be messenger RNA based, a relatively new type of vaccine. The tech makes sense. Any smart medical/biotech types in here have any input on the safety of these types of vaccines? Looks like efficacy seems to be there...?
#3
mRNA technology is (relatively) new, but was rapidly building momentum well before covid.
In previous studies and trials it tended to work well with no unexpected side effects, in both humans and animals.
Some people confuse DNA and RNA. mDNA pharma has at least the potential to cause undesired DNA changes in the host which could be dangerous. mRNA does not, since it doesn't engage with the subject's own DNA. So no reason to think that mRNA has any particular risk of unanticipated side effects.
In previous studies and trials it tended to work well with no unexpected side effects, in both humans and animals.
Some people confuse DNA and RNA. mDNA pharma has at least the potential to cause undesired DNA changes in the host which could be dangerous. mRNA does not, since it doesn't engage with the subject's own DNA. So no reason to think that mRNA has any particular risk of unanticipated side effects.
#4
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mRNA technology is (relatively) new, but was rapidly building momentum well before covid.
In previous studies and trials it tended to work well with no unexpected side effects, in both humans and animals.
So no reason to think that mRNA has any particular risk of unanticipated side effects.
In previous studies and trials it tended to work well with no unexpected side effects, in both humans and animals.
So no reason to think that mRNA has any particular risk of unanticipated side effects.
This sounds like pure BS. Having no long term data on side effects that may manifest themselves later on, there is definitely a risk of unanticipated side effects, just like when you put any foreign substance into your body. Unless you have 5, 10, 20 years of data on it, you have no basis on your claim that there is no reason to think that there is a risk. It’s a risk just based on that alone.
Also, pharmaceutical companies have a long history of squashing any bad data that comes out about their products, so it may take even longer than that to know the true damage done by this vaccine. The J&J talcum powder lawsuit is a prime example of that. There are many other examples as well.
#5
This sounds like pure BS. Having no long term data on side effects that may manifest themselves later on, there is definitely a risk of unanticipated side effects, just like when you put any foreign substance into your body. Unless you have 5, 10, 20 years of data on it, you have no basis on your claim that there is no reason to think that there is a risk. It’s a risk just based on that alone.
Also, pharmaceutical companies have a long history of squashing any bad data that comes out about their products, so it may take even longer than that to know the true damage done by this vaccine. The J&J talcum powder lawsuit is a prime example of that. There are many other examples as well.
Also, pharmaceutical companies have a long history of squashing any bad data that comes out about their products, so it may take even longer than that to know the true damage done by this vaccine. The J&J talcum powder lawsuit is a prime example of that. There are many other examples as well.
But they've been playing with mRNA for about 30 years and haven't seen any ill effects. If you knew anything about biology (you clearly don't) you would understand what RNA does, and does not, do in your body. It is a very precise, targeted biochemical intervention.
But it's certainly a free country, nobody here in the US is going to force you to get a vaccine. If the government tried to mandate that, I'd go to bat for you. Other countries won't be as considerate.
But the good news: we're about to get vast quantities of real-world data on mRNA vaccines. That's actually a good thing because they also have the potential to treat or even vaccinate against cancer (that's actually what scientists have been REALLY interested in doing with mRNA).
The talc powder thing appears to be a masterful case study of ambulance chasers snowing ignorant juries. My wife did the research, because her mom actually died of ovarian cancer, but she concluded it was all BS. No statistically significant data, and the noise that was there appeared to have been relying on very poor science: study participants' memory, after the fact, as to how often and how long they used the product over decades. The better controlled studies found nothing.
#6
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Joined APC: Mar 2020
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Obviously, we aren’t going to wait 5, 10, 20 years. I’m likely going to be at the front of the line as an EMS provider, and I’m trying to figure out how safe the tech likely is before I raise my hand.
I know that mRNA tech has been used in cancer meds for a while, but this is its first foray into battling a pathogen. It makes a whole lot of sense—code a string of mRNA, inject it as a more stable form, let it break back down to mRNA, high five with some ribosomes and crap out proteins that will trigger a specific immune response. mRNA doesn’t last long, so it will degrade soon after translation.
I’m not a cellular biology expert, but it seems to me like the issue could be where the stabilized form of mRNA turns back into mRNA in the body? If that goes sideways, and the codons get f’d up, it could maybe result in the wrong/no polypeptide being created?
Just thinking aloud.
I know that mRNA tech has been used in cancer meds for a while, but this is its first foray into battling a pathogen. It makes a whole lot of sense—code a string of mRNA, inject it as a more stable form, let it break back down to mRNA, high five with some ribosomes and crap out proteins that will trigger a specific immune response. mRNA doesn’t last long, so it will degrade soon after translation.
I’m not a cellular biology expert, but it seems to me like the issue could be where the stabilized form of mRNA turns back into mRNA in the body? If that goes sideways, and the codons get f’d up, it could maybe result in the wrong/no polypeptide being created?
Just thinking aloud.
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