Vaccine wastage...
12-12-2020, 01:56 PM
#1
Perennial Reserve
Thread Starter
Joined APC: Jan 2018
Posts: 11,480
Vaccine wastage...
For those trying to calculate how far the limited production runs of newly certified vaccines will go, don’t forget the wastage factor. Example:
Granted, the US with FedEx/UPS typically does fairly well on medical logistics compared to the third world, but that still doesn’t mean you can reasonably expect to immunize 50 million people with 100 million doses (at two doses per person), and worldwide that’s definitely not the case. And with vaccines requiring storage at -90 degrees F, the wastage might be substantial in even a fair number of first world countries.
https://moodle.digital-campus.org/mo...ew.php?id=8097
Vaccine wastage rates and wastage factors
Some vaccine doses may be wasted during the year for various reasons. The wastage rate is the percentage of vaccine doses that are wasted. The general guideline on the amount of vaccine wastage that is considered acceptable for different types of vaccines is also shown below:Vaccine wastage
Some reasons for vaccine wastage:- Some unused doses may have to be thrown away, e.g. because they have passed their expiry date or lost their labels.
- Some doses may be spoilt for one reason or another (e.g. vaccines damaged by storage at the wrong temperature).
- Some vials or ampoules may be broken during transport and handling.
- For liquid vaccines supplied in single or two-dose vials (e.g. pentavalent vaccine and PCV10), a wastage rate of 5% is acceptable.
- For OPV, a wastage rate of 10% is considered acceptable.
- For liquid vaccines supplied in multi-dose vials of 10 or more doses, a wastage rate of 15% is acceptable.
- For reconstituted vaccines, wastage rates of 50% for BCG and 25% for measles vaccine are considered acceptable.
https://moodle.digital-campus.org/mo...ew.php?id=8097
12-12-2020, 08:01 PM
#2
Gets Everyday Off
Joined APC: Aug 2016
Position: Relaxed
Posts: 6,929
If I am not mistaken, the higher wastage rates are based on a vaccine vial sitting in a doctor’s refrigerator until it expires. Like buying a gallon of milk when you only use it for a cup of coffee in the morning.
Mass inoculations (think the initial Salk vaccine shots) had little of this wastage.
Mass inoculations (think the initial Salk vaccine shots) had little of this wastage.
12-13-2020, 07:43 AM
#3
Perennial Reserve
Thread Starter
Joined APC: Jan 2018
Posts: 11,480
Results
The overall wastage rates for almost all vaccines were higher in Kangra district (BCG 37.1%, DPT 32.1%, Measles 32.2%, OPV 50.8%, TT 34.1% and pentavalent 18.4%) than Pune district (BCG 35.1%, DPT 25.4%, Measles 21.7%, OPV 14.3%, TT 23.1% and pentavalent 13.2%). Wastage for pneumococcal conjugate and measles-rubella vaccines in Kangra district were 27 and 40.5%, respectively. With transition from 5- to 10-doses vials for rotavirus vaccine, wastage at stores levels increased in both Kangra (29 to 33.2%) and Pune (17.8 to 25.7%) districts. With transition from intramuscular to intradermal fractional inactivated polio vaccine, the wastage increased from 36.1 to 54.8% in Kangra and 18.4 to 26.9% in Pune district.Conclusions
The observed vaccine wastage rates for several vaccines were relatively higher than program assumption for forecasting. The observed variations in the vaccine wastage indicates need for state or region based documentation and monitoring in India for appropriate programmatic action.wastage rates are higher than you would think. Google it. There’s plenty of literature out there. Except for the Chinese - who claim 2-3%, 5-15% is pretty common. And the more you try to do quickly, the higher it tends to climb. And anything that needs to be stored at -90F greatly complicates matters.
12-13-2020, 08:11 AM
#4
Speed, Power, Accuracy
Joined APC: Sep 2007
Position: PIC
Posts: 1,699
Originally Posted by Excargodog
https://bmcpublichealth.biomedcentra...89-020-08637-1
wastage rates are higher than you would think. Google it. There’s plenty of literature out there. Except for the Chinese - who claim 2-3%, 5-15% is pretty common. And the more you try to do quickly, the higher it tends to climb. And anything that needs to be stored at -90F greatly complicates matters.
wastage rates are higher than you would think. Google it. There’s plenty of literature out there. Except for the Chinese - who claim 2-3%, 5-15% is pretty common. And the more you try to do quickly, the higher it tends to climb. And anything that needs to be stored at -90F greatly complicates matters.
12-13-2020, 08:20 AM
#5
Perennial Reserve
Thread Starter
Joined APC: Jan 2018
Posts: 11,480
Originally Posted by GeeWizDriver
And here's an interesting thought. What happens if you take the needle and the dose you are given just happens to be one of those that got left out of the fridge for juuuust a little too long....? And is it -90° when it goes in your arm?
12-13-2020, 08:25 AM
#6
Speed, Power, Accuracy
Joined APC: Sep 2007
Position: PIC
Posts: 1,699
Originally Posted by Excargodog
-90 for storage. Not administration. Still, anything that complicates the logistics chain tends to drive wastage up.
A fluid at -90° would be a little tough to inject. C'mon man!
12-13-2020, 08:34 AM
#7
Prime Minister/Moderator
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,211
Originally Posted by GeeWizDriver
And here's an interesting thought. What happens if you take the needle and the dose you are given just happens to be one of those that got left out of the fridge for juuuust a little too long....? And is it -90° when it goes in your arm?
Of course the technician handling the stuff would have his/her hands frozen before it ever got to that point.
12-13-2020, 08:39 AM
#8
Perennial Reserve
Thread Starter
Joined APC: Jan 2018
Posts: 11,480
https://apps.who.int/iris/bitstream/....Rev.1_eng.pdf
The World Health Organization reports over 50% vaccine wastage around the world. Despite the availability of many tools for reducing such wastage, high wastage rates are still occurring in countries. Because of increasing EPI vaccine costs during the last two years, tightening vaccine security and the introduction of new and underused vaccines through the Global Alliance for Vaccines and Immunizations (GAVI), countries are looking more closely than before at vaccine wastage. Moreover, GAVI has requested countries to bring down vaccine wastage rates: “The country would aim for a maximum wastage rate of 25% set for the first year with a plan to gradually reduce it to 15% by the third year. For vaccine in single-dose or two-dose vials the maximum wastage allowance is 5%. No maximum limits have been set for yellow fever vaccine in multidose vials.”1
This document reviews the factors affecting vaccine wastage and discusses the tools available for reducing wastage and their relationships to each other, with the aim of providing assistance to programme managers to establish a system for monitoring vaccine wastage as a programme quality indicator.
Vaccine wastage can be expected in all programmes. The questions arise as to whether any of the wastage is preventable and, if so, how to prevent it. Wastage in unopened vials is usually attributable to cold chain and stock management problems and can be minimized. Wastage in opened vials cannot be eliminated, but can be reduced by the introduction of the multidose vial policy (MDVP), the effective use of vaccine vial monitors (VVMs), and improved immunization strategies and practices.
Vaccine wastage is an important factor in calculating vaccine needs. If incorrect figures are used the country concerned may face serious vaccine shortages or be unable to consume received quantities, leading to increased wastage through expiry.
This document reviews the factors affecting vaccine wastage and discusses the tools available for reducing wastage and their relationships to each other, with the aim of providing assistance to programme managers to establish a system for monitoring vaccine wastage as a programme quality indicator.
Vaccine wastage can be expected in all programmes. The questions arise as to whether any of the wastage is preventable and, if so, how to prevent it. Wastage in unopened vials is usually attributable to cold chain and stock management problems and can be minimized. Wastage in opened vials cannot be eliminated, but can be reduced by the introduction of the multidose vial policy (MDVP), the effective use of vaccine vial monitors (VVMs), and improved immunization strategies and practices.
Vaccine wastage is an important factor in calculating vaccine needs. If incorrect figures are used the country concerned may face serious vaccine shortages or be unable to consume received quantities, leading to increased wastage through expiry.
12-13-2020, 12:05 PM
#9
Speed, Power, Accuracy
Joined APC: Sep 2007
Position: PIC
Posts: 1,699
Originally Posted by rickair7777
Nothing. It would instantly freeze the tissue solid at the injection site, blocking any further injection. You'd have a tiny little pin-prick freeze burn.
Of course the technician handling the stuff would have his/her hands frozen before it ever got to that point.
Of course the technician handling the stuff would have his/her hands frozen before it ever got to that point.
Lighten up.
Thread
Thread Starter
Forum
Replies
Last Post
