Covid Treatment Development
11-05-2021, 08:49 AM
#21
Gets Weekends Off
Joined APC: Nov 2020
Position: Enoch Powell Enthusiast
Posts: 2,121
Originally Posted by rickair7777
Source? Pfizer did say the pricing would be tiered for less-affluent countries. And like the vaccines, various nations have already placed large orders pending certification.
https://www.nytimes.com/2021/11/05/h...ovid-pill.html
From the article:
"The U.S. government has been in negotiations with Pfizer for enough pills for 1.7 million courses of treatment, with an additional option for 3.3 million, according to a senior administration official. That is about the same quantity that the United States has ordered from Merck. The government expects to pay about $700 per treatment course for both drugs, the official said."
from the same article (general interest):
"Pfizer said it expects to be able to produce enough pills for more than 180,000 people by the end of this year and for more than 21 million people in the first half of next year. Merck, too, has said it plans to ramp up production over the next year."
Last edited by DeltaboundRedux; 11-05-2021 at 09:00 AM.
11-07-2021, 06:42 AM
#22
Prime Minister/Moderator
Thread Starter
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,271
WSJ published an article today on heart inflammation associated with mRNA vaccines. It's being studied; possible theories being investigated include spike protein interaction, inflammation from the mRNA itself, and incorrect injection into a vein (instead of muscle where it's supposed to go).
877 confirmed cases, out of 87M doses delivered in the US. Almost all young men under 30, and almost all recover quickly. Moderna appears to carry a higher risk than pfizer, possibly due to higher levels of mRNA in each dose. The article reports that the risk/benefit is still in favor of getting the vaccine, even for young men (or just get J&J).
It would quite convenient if the problem is poor injection technique, that's easy to fix.
877 confirmed cases, out of 87M doses delivered in the US. Almost all young men under 30, and almost all recover quickly. Moderna appears to carry a higher risk than pfizer, possibly due to higher levels of mRNA in each dose. The article reports that the risk/benefit is still in favor of getting the vaccine, even for young men (or just get J&J).
It would quite convenient if the problem is poor injection technique, that's easy to fix.
11-07-2021, 08:10 AM
#23
:-)
Joined APC: Feb 2007
Posts: 7,339
Originally Posted by rickair7777
WSJ published an article today on heart inflammation associated with mRNA vaccines. It's being studied; possible theories being investigated include spike protein interaction, inflammation from the mRNA itself, and incorrect injection into a vein (instead of muscle where it's supposed to go).
877 confirmed cases, out of 87M doses delivered in the US. Almost all young men under 30, and almost all recover quickly. Moderna appears to carry a higher risk than pfizer, possibly due to higher levels of mRNA in each dose. The article reports that the risk/benefit is still in favor of getting the vaccine, even for young men (or just get J&J).
It would quite convenient if the problem is poor injection technique, that's easy to fix.
877 confirmed cases, out of 87M doses delivered in the US. Almost all young men under 30, and almost all recover quickly. Moderna appears to carry a higher risk than pfizer, possibly due to higher levels of mRNA in each dose. The article reports that the risk/benefit is still in favor of getting the vaccine, even for young men (or just get J&J).
It would quite convenient if the problem is poor injection technique, that's easy to fix.
037K20A
029L20A
012M20A
024M20A
027L20A
015M20A
025L20A
026A21A
013M20A
016M20A
022M20A
030L20A
026L20A
007M20A
013A21A
011A21A
031M20A
032L20A
010A21A
011J20A
030A21A
028L20A
011L20A
004M20A
025J20-2A
041L20A
011M20A
031L20A
11-07-2021, 09:15 AM
#24
Prime Minister/Moderator
Thread Starter
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,271
Originally Posted by Mesabah
It appears that the adverse reactions are all from a handful of lot numbers. This strongly indicates a quality control issue. For example, only these lot #'s from Moderna, the 4000+ other lots contain zero.(the CDC now gives AE data by lot #)
11-08-2021, 08:28 AM
#25
Prime Minister/Moderator
Thread Starter
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,271
Regeneron's anti-body therapy prevents covid for up to eight months after dosing. It's original intended use was as a therapeutic, but with this duration it might be suitable as a "vaccine substitute".
Biochemically, it's more straight-forward than triggering your body's immune system to make the antibodies. Does require an injection in a clinical setting. Maybe anti-vaxxers will be OK with this, since it's just inserting pharma into your body (like taking advil), as opposed to tampering with your body to produce the immune response.
https://www.reuters.com/business/hea...19-2021-11-08/
Biochemically, it's more straight-forward than triggering your body's immune system to make the antibodies. Does require an injection in a clinical setting. Maybe anti-vaxxers will be OK with this, since it's just inserting pharma into your body (like taking advil), as opposed to tampering with your body to produce the immune response.
https://www.reuters.com/business/hea...19-2021-11-08/
12-01-2021, 07:44 AM
#28
Gets Weekends Off
Joined APC: Nov 2020
Position: Enoch Powell Enthusiast
Posts: 2,121
https://www.washingtonpost.com/healt...ck-covid-pill/
FDA advisers narrowly recommend authorization of first antiviral pill to treat covid-19
---------
TLDR; 13-10 vote, non binding for the FDA. Those who voted no were concerned that statistically the the benefit is minimal, if any. Safety is an issue; concern that this could just lead to a worse variant of Covid.
FDA advisers narrowly recommend authorization of first antiviral pill to treat covid-19
---------
TLDR; 13-10 vote, non binding for the FDA. Those who voted no were concerned that statistically the the benefit is minimal, if any. Safety is an issue; concern that this could just lead to a worse variant of Covid.
12-09-2021, 07:25 AM
#30
Prime Minister/Moderator
Thread Starter
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,271
https://www.newsnationnow.com/health...body-cocktail/
FDA approves AstraZeneca MCA cocktail.
It's actually not approved for use as a therapy, but rather a preventive in lieu of vaccines. Useful for those with compromised immune systems, or vaccine allergies. Protection for several months to one year, didn't mention what the efficacy is. Not sure it's available for anti-vaxxers, may need some medical history.
FDA approves AstraZeneca MCA cocktail.
It's actually not approved for use as a therapy, but rather a preventive in lieu of vaccines. Useful for those with compromised immune systems, or vaccine allergies. Protection for several months to one year, didn't mention what the efficacy is. Not sure it's available for anti-vaxxers, may need some medical history.
Thread
Thread Starter
Forum
Replies
Last Post
