The real risk in 135 night freight is severe Wx (icing, CB's, or both), particularly in mountainous terrain. One or two engines doesn't matter much here, although turbines have more potential when the poo hits the fan.

A piston engine in these conditions is like a old-style single-shot pistol on Saturday night....per Steve Earl, it can get you into trouble, but it can't get you out.

This sort of flying will enhance your skills and resume, but no matter how skilled you are, there is an inherent risk (and a relatively high one) of encountering trouble beyond the airplane's ability to overcome. It's a matter of luck...if it happens to you, you will probably die.

After doing the research, I opted out of night freight and stuck with MEI work which at least gave me a lot of twin time. But I was older with a family, and had already expended up a few of my nine lives in the military.

Basically it depends on your personal situation, and what other opportunities you have. But if you have children, please don't do it.

Classic.

I can laugh at that because it happened to me. :D

If you do the single-pilot night freight thing, don't do it in the winter. Thunderstorms should be respected. Ice should be feared.