Another delayed lockdown effect…

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Quote: Some here definitely overdue for a colonoscopy.
Or as I say, an inspection of their tonsils starting from the rear and working up.
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Everybody loves a good butt joke, but it really is a life and death issue.

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Patients whose cancer was detected by screening colonoscopy or FOBT had substantially higher overall survival and CRC specific survival 5 years after diagnosis (>85% and >90%, respectively) than patients whose cancer was detected by symptoms or otherwise (<70% and <75%, respectively). After adjustment for age, sex and education, patients whose cancer was detected by screening colonoscopy had a 65% lower total mortality than patients with symptom-detected cancers (hazard ratio, HR, 0.35, 95% confidence interval, 95% CI, 0.24-0.50) (Table (Table3).3). A 50% mortality reduction persisted even after additional control for stage and location of the cancer (HR 0.50, 95% CI 0.34-0.73)
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Results We analysed 1747 patients who died from colorectal cancer and 3460 colorectal cancer-free controls. Compared with no endoscopic screening, receipt of a screening colonoscopy was associated with a 67% reduction in the risk of death from any colorectal cancer (adjusted OR (aOR)=0.33, 95% CI 0.21 to 0.52). By cancer location, screening colonoscopy was associated with a 65% reduction in risk of death for right-colon cancers (aOR=0.35, CI 0.18 to 0.65) and a 75% reduction for left-colon/rectal cancers (aOR=0.25, CI 0.12 to 0.53).

Conclusions Screening colonoscopy was associated with a substantial and comparably decreased mortality risk for both right-sided and left-sided cancers within a large community-based population
And that applies equally to mammograms, Pap smears…even childhood immunizations which got backlogged during the lockdowns.
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I agree. Cancer screenings are important and life savers.
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Quote: Coming soon to Covid…
https://pubmed.ncbi.nlm.nih.gov/34384810/
"enhancing antibodies have a higher affinity for Delta variants" is not the same as "high enough to be a problem".

Like Boiler said, we'd have seen it by now.
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Quote: "enhancing antibodies have a higher affinity for Delta variants" is not the same as "high enough to be a problem".

Like Boiler said, we'd have seen it by now.
You mean, like the case fatality rate in Britain is now HIGHER for fully vaccinated than unvaccinated?
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Quote: You mean, like the case fatality rate in Britain is now HIGHER for fully vaccinated than unvaccinated?
Not a real apples to apples comparison if fully vaccinated 80 year olds versus unvaccinated 10 year olds. You need to correct for age before having a valid comparison. Even before COVID elderly people in long term care facilities had an ANNUAL mortality of 35%. At a certain point in anyone’s life even a common cold might put them over the edge.

By and large, COVID non naive people (vaccinated or infected and recovered) are going to handle an infection much better than their age matched naive comparisons, but having a degree of immunity to COVID don’t make anyone immortal…
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Perhaps. But given what is starting to happen in Israel, Britain, Iceland, and elsewhere, it seems to me ADE is real and is going to be a problem.
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Quote: Perhaps. But given what is starting to happen in Israel, Britain, Iceland, and elsewhere, it seems to me ADE is real and is going to be a problem.
For the three immunizations for which ADE was significant, respiratory syncytial virus, a very early experimental measles vaccine, and one serotype of dengue, it made its appearance known early and unequivocally.

You can never say never, but at present there is no real evidence these immunizations are a problem with ADE and the risk lessens everyday that no problem is identified.
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