FedEx actually did a pretty good job in standardizing the MD-11 cockpits...the only real differences I've seen is the placement of the weather radar/ACARS printer...but nothing earth shattering.
The MD-10s are all the same...they pretty much re-did the entire DC-10 cockpit, so they could make them exactly the same.
As far as flying differences? Well, there are those that say our MD-10 accident in Memphis may have been exacerbated by the crew not flying the MD-10 a whole lot.
Personally, in the past 2.5 years, I've flown the MD-10 MAYBE 10 legs?? Out of 200+ legs total?? And most of those were during IOE...
Landing is critical...different techniques (not officially taught, of course...because it's a common type-rating and lands just like an MD-11 right?
) . If you land it like an MD-11, you'll smack it on...kinda sounds like the MEM accident, eh?