I believe that many of these requirements just serve as a filter for HR and is directly related to supply and demand.
Flying is flying.
I've read posts on other boards from guys whining that “small aircraft” (their words, not mine) guys have a hard time transitioning to bigger airplanes and new areas of operations. There was even one guy that mentioned the lack of CPDLC experience for some new-hires. I watched the training captain use CPDLC one time and then like I do with every other new toy, I played around with it in-flight and figured it out. If you have the ability to learn, long-haul/wide-body flying is barely a transition.
I'm a former Part 135 GA aircraft guy, former turbo-prop, former RJ, former A320 and now A330/A340. My most difficult transition was from GA aircraft to the Dash-8. Every other transition was easier than the one before it. Using the HF radio and CPDLC for hours over the water is straightforward. After impacting the ground a few times, I learned to flare at 40’ instead of 20’. The real trick with long-haul flying is learning how to pace yourself in-flight and finding ways to fight off boredom.