I'm sure it will be painful in the begging. However, take Delta for example. The pilot contract has many provisions that are at least or more restrictive then this new rule.
It will affect the regional side more than anything. I believe that there will be a day soon within the next few years that people give up on the whole pilot thing. When they see that the job just consumes too much time for too little pay. That's when you will see the companies step up and do the right thing. The pay is already about as low as it can get. The job will have to become more attractive again. It really has let itself go.
Something has got to give.