Dude, it doesnt have to be a small city or airport to be relegated to commuting on RJ's. I live in MCI and 99% of the time I am on RJ's.
Advice..
1) know your contract and commuter clause.
2) check loads on all airlines
3) Pre list for all jump seats.
4) Have a good app on your phone to allow you to look at flights (next flight, eskyguide.com, passrider, etc)
5) know all the hotels in your base that you are comfortable with the price and look for discount codes.
6) Dont be afraid to go early.
7) Fed Ex, UPS
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