LoneStar,
If you think staying in shape on a ACMI schedule is hard, try a Regional... I've done both and I miss the 2-3-4 days sit at the hotel where I could spend time on a good workout. Aside from the pain of leaving the family behind, the "17 days" is great, and the backside of the clock didn't really affect me when there was a 9 hr time change.
Try the Regionals with 11/12 days off and the other 19 working all day with limited time at the hotels. There is some good advice in this thread, diet + exercise is good, but even exercise without the diet helps, you increase the metabolism and burn more calories. My $ 0.02.