I thought I remember reading an article where a passenger actually got in trouble for making a remark like that about the crew at one point? Maybe it's just wishful thinking.

If I'm jumpseating (going home) I would explain to her how inappropriate she is being right now. I would then tell her I'm going to get a law enforcement officer to come discuss this allegation with us. I would then walk away, only to come back a few minutes later and just sit somewhere else. I wouldn't ever actually get an officer. It would be just enough to get them worried.

If I'm working the flight I would actually get a LEO (stressing an actual LEO, not the badge carrying, smurf dressing, officer pretending kind) and have them make sure I'm am 100% good and get it on paper. I would then ask the LEO to explain this to her, and scare her as much as possible that she is close to being in trouble. I would then do everything in my power to deny her boarding on my flight. I don't want a passenger that is thinking I'm drunk being on my plane with the potential to cause havoc. Also, it would make me feel better knowing she is having to suffer at least a little.