I think going to VX is a risk. Because its a start up, there is a big risk that it might not make it. But on the flipside, if it does make it, you are sitting pretty with some nice seniority.
I personally think VX will make it. They provide a superior product, and all my friends that have flown on them (as paying passengers) loved the experience. Maybe my views are skewed because my background is in hotels, and guests will pay a premium for better amenities, whereas airline passengers just want to the cheapest ticket.
to the OP, with the very little information you put out there, I would highly recommend you going to VX as opposed to sitting in the right seat of a regional. Even if it is, in the E190. At the very least, you will have time in a larger aircraft, and possibly a type on an A320. So if VX does go under, at least you will be more marketable. Besides, is a regional airline any more stable the VX??
Good luck. I would also take into account where you live. Commuting is for the birds.