We, as pilots, can always commute for a job. I've told my fiancée I'd move (within reason) where she could get a job she enjoys.

QOL isn't great in the best cases when commuting. So if you can make a change early on where you won't take a huge hit in seniority to make life easier... Why not try? You may not get the base you want from the start, but at least it will be an option in the future

Best of luck!!