Okay, I'm gonna get blasted on this one but...Skymaster 337. Perfect for the low time pilot/owner/operator. I used to fly one for a machine shop when I was in college and the owner flew it himself about 30 hours a year. At least I didn't have to worry about it rolling over on him when he lost an engine!
Couple of quirks - the rear engine can overheat because of quirky cowl flaps, and the gear has a ton of actuators that need to be kept tweaked but overall I really like the airplane. At gross on a cool day you can eek about a 150 fpm climb on just the rear one. If you lose the rear one, find a spot to land.
I owned a flight school in MI in the late 90's and since I had gathered a bunch of time in these things the Detroit FSDO sent all those needing "training" in the 337 my way. So I got to see quite a few of them - good, bad, & ugly. I would buy one but my wife thinks they're ugly.