You don't say whether you have your ATP. I was in a similar situation years ago. I went and got a single engine ATP. With that, my test never expired, I looked that much more qualified and got a job with a dirt bag regional. One year in the Rt. seat and two in the left and I was very competitive.
I believe we are only one year away from rapid hiring by the majors. That will mean fast upgrades at the regionals. You need to be flying for one when the time comes.
Good luck.