Not true. I spent 9 years at a regional and was very senior at 9 year CA in the RJ. Now I'm at a major and make the same as a second year FO as I did as a 9 year CA AND get the same days off with about 50 legs less flown per month. I can get more days off too if I wanted. My quality of life improved the day I quit the regional airline. It was also gained faster than at the regional. I know not all majors are the same, but my QOL has improved more than I could have wished for. Why go to the majors? Pay, equipment, and QOL.