I would advise taking the route that got you there quickest.

Get to where you want to be ASAP. Frankly, get to where you can forge a decent career, ASAP, it doesn't have to be your first choice.

When you're there, dig your heels in, and make it your home for the next 35 years. In that time, things will go up, and things will come down. You will be rewarded with seniority based pay, and seniority based quality of life, and increased security. The grass is always greener, but the rolling stone gathers no moss, as they say.

Don't worry about the next big thing, because the tide ebbs and flows. Relax, enjoy the journey, and protect yourself. There are far too many folks flying short term contracts around the globe, hopping from one job to the next to keep a roof over their families' heads, with no benefits, no retirement etc. because they repeatedly jumped ship, and never created any seniority-based protection for themselves. Many would have been better off staying at a regional, all things considered.

As you can see, I'm very conservative in my outlook on this matter, but if history is of any value, the best we can do is endevor to protect ourselves. In this industry, seniority is an enormous part of that.

Perhaps not a very useful reply.