Little different point of view. Your TPIC time is low for total hours. Do you have your ATP? I would get that out of the way and apply to a regional. If the fabled shortage comes up in December (age 65 rule) movement will start from the regionals first. Getting that 121 time will make you much more competitive to a major. That is where the majority of your competition will be from. That is where your time goes up really fast. Just my two cents