Personally, I'd go for Ramstein, but a lot depends on your situation. Are you married? Kids? What rank? Career goals?
I was stationed at Ramstein for 3 1/2 years and loved it. Traveled all over Europe with my wife. Lots of good flying to unusual places. However, some won't like it if they have small kids -- plenty of folks do it and adapt, but a lot of folks find it easier stateside with small kids.
Macdill has CENTCOM, so if you are more senior and want to go the joint staff route there may be some options there for you. If you don't have those aspirations, there may also be some (involuntary) options there for you.
Good luck with the decision.