Anything is possible, especially if a severe pilot shortage occurs (where legacies have trouble manning flights). However...

You may get several opinions on this, here is mine and I'm sure someone will violently disagree but this is a tough one to call.

All the good aside, and despite all the time that passes I think your problem here is going to be how a company would view the risk of public exposure in the media after an accident, and how this background could be played in a civil lawsuit. The DUI is bad, but it was a long time ago and people understand that we are all human. But the real gotcha here is going to be the pilot license revocation and driving with a suspended license...frankly I think major airlines are going to consider that too over the top to risk possible media exposure.

I suppose it's possible that you'd get on with a lower end national airline, but honestly in your shoes I'd probably hang on to that good corporate job, and keep your corporate network humming in case you ever need to find another job. Corporate operators are far more likely to hire you based on who you are today as opposed to who you were as a teenager, or how you'll look in a USA Today expose on airline pilot backgrounds.