Originally Posted by Ultralight

Multiple checkride busts may raise an eyebrow at your first 121 gig. They don't want to spend thousands of $$$'s and hours of precious sim time only for you to flunk out of training. I think most regionals will turn a blind eye to 1 or 2 busts, but 3 or more may take some explaining.
Once you have a few years of uneventful 121 checking events though, I doubt the majors care if you screwed up a lazy 8 on your commerical.
I personally think it's good for a pilot to fail a checkride. Those that have busted Know what a humbling experience it is and aren't so cocky or complacent the next time they climb into the cockpit.