i have tried to do homework in the airplane but with short legs on the crj200 its almost impossible. i break out the laptop and try to read my online assignments if im the PF. if im the PNF it gets a little distracting in busy airspace with the radios. trying to study on an overnight just isnt going to happen unless youre a hermit.
i would say a lot of it also depends on how intense the classes you take are. if its light reading, and small assignments its doable. but the downside to that would be your final would probably be pretty heavily weighted, meaning youd need to do some serious cramming at the end.