I disagree with allot of the comments here. Sometimes its best to find a crappy regional with lots of movement. Off reserve quicker, upgrade quicker and get the hell out of there quicker.
Quality of life can be improved by seniority and the extra income upgrade brings.

Good companies (Skywest etc) have too many happy campers who have no intention of leaving. That means long reserve for new hires and 5+ year upgrade.

There are two sides to the argument.