Comair used eMaestro for the daily scheduling, and it seemed to work great. No real complaints about it after they added in the extra features.
When it came to PBS, Comair used a very archaic system (maybe made by SBS?). While it was clunky and required using odd/old style syntax entries, I usually got exactly what I wanted every month.
CRJ side of ExpressJet uses Sked+ which is okay I guess. It seems slow to accept changes to schedules, and changes aren't readily shown. But it seems to work okay.
When it comes to PBS, Flica seems overly complicated. Almost too many choices/scenarios that can easily bid you into a black hole.