Some newbie questions.

-What are the odds of Ameritflight pilot making it to Majors straight without going regionals? Or is regional necessary or recommended steps before major? I'm asking if its common as I'm sure anything is possible.

-if going to Major from ameritflight is common, big disadvantage during training and interview compared to regional guys? I ask because RJ would be close to major jets than the planes at Ameritfligt.

Thank you!