Can't imagine why anyone would want to pick up any of these flights (actually I can, but they're not good reasons) but especially 245/2. Almost 11 hour duty day(night) EWR -IND-BOS-EWR w/o hotel in IND and no catering. You either eat or sleep in IND but not both. Throw in deicing in all three locations and it sounds very fatiguing to me.