Sure can. When I flew C-21s (Lear 35), we had a guy flying a jet up to LFI one night and he accidentally landed at PHF. It was a CAVU night, but sometimes it really helps to have that localizer dialed in.

I flew up to RAP one day and we both had a double take when we saw both RAP and RCA's runways lined up. Sure enough, a few months later a regional jet landed at RCA by mistake...easy to do there if you get even a bit complacent.

Not sure what happened in this case, but seems easy to confuse the runways there.