Reserve pilots get 12 days off per month.
In response to sgrd0q's question about the 757. If you live near the airport then reserve is no big deal if you don't mind not having more than 12 days off a month. As far as upgrade is concerned, the 757 is much more senior than the 737. The bottom 737 captain is EWR based and hired in 1998 while the bottom 757 Captain in EWR was hired in 1987.
Line quality and days off for more junior pilots is much better in the 737.