Tuckster - I agree with these guys. Go do what makes you happy.
I left Comair in 2004 to take care of my father who had terminal cancer. After he passed, there weren't many places to look for a good flying job. I owned a business for a couple of years, sold it, and now work for a medical company. I miss flying too much, and am starting my job search again - even though a regional job will be an 80% pay cut. But life is short and if flying is what you got to do, then do it. The rest will take care of itself.