In my opinion, fractional flying is still an unknown quantity to the airline world. If you have done both you know that the unpredictability of and the type of flying a fractional pilot does daily requires a skill set that would be a huge benefit to the IROP's the 121 world sees from time to time.
Give it some time, and hopefully the first few don't give us a bad reputation, and the airlines will be looking for seasoned fractional pilots.