I don't live in Europe but travel there extensively. Commuting is doable, but it all depends on how much you are willing to commute.

In the beginning before you have any seniority plan to spend only one or two days at home tops. Once you can hold a line things will be better.

I know of people who commute from Alaska to ORD and JFK which is much, MUCH worse than a commute from Western Europe to the American East Coast.

I also know of flight attendants who live in Brazil and commute to MIA, a pilot who lives in Ireland and commutes to JFK, among others.

So it is not impossible. Like I said before, just be ready to be away from home quite a bit while on Reserve.