First of all what's wrong with Great Lakes? Have you ever been there? I haven't, so I don't express opinion of a company that I don't know.

Lakes, today, is looking for pilot with 500tt and 20 multi (desired) according by the ad that was on the website findapilot.com.

In order to build 1200 for AMF or ATP min in order to apply to a regional you generally have two option, CFI for a part 141 school, so that you can build time fast, but they pay 15-20$ an hour or go for several jobs around, flight time and pay are really variable.
So the point is, if you are willing to make 15$/hr flying as a CFI why not making the same money flying a TURBINE plane multi crew, operating both part 135 and 121 logging 100hrs a month?
For low time people I'd suggest a talk to Lakes recruiter.

How good is the company? I don't know.