Runway lighting is standardized, so if a 121 operator can go there, it should be adequate. You (or the tower) can adjust the intensity of the runway/ALS lights as needed.
Taxiway lighting is more likely to be an issue (taxiway lights can be weak or NOTAMed OOS but the taxiway can still be used I think). The complexity of the airport layout is what really creates confusion (ORD, DFW, LAX)