You have to realize that working in the airline industry in general is a gamble. You could loose your medical or get furloughed at any time with no notice. Go somewhere that has a base in a city you want to live where you can enjoy your life outside the airline. Life is too short to not be happy, so go somewhere that will allow you to be happy outside of "work". You may not realize it now, but the novelty of being an airline pilot will wear off. No one thinks we are as cool as we think we are, it is not glamorous anymore. Find somewhere with a base you like, and enjoy the fact that you're not driving a desk like most of your friends