Training is 6-8 weeks in SLC, so you'd be gone for awhile at first. Especially combined with the initial assignment if you don't live in ORD or MSP.
As far as how many nights away from home? That varies. I had months on reserve where I only spent 1-2 nights away, I worked like a dog every day and was pretty much useless, but I was home. Then there was months where I spent 13+ nights in a hotel (many on TDY, just sitting).
As a lineholder I average more nights away from home each month, but have more total days off and am not nearly as wore out. Life is better.
It's still a regional, so you can't be that excited or comfortable. Don't come to SKW unless you can get off reserve within 6 months, otherwise it will begin to consume your soul.