Hmmmm,
Have you done a "repair permissions" lately with Disk Utility? This is a freebie with no harmful consequences that should be done every so often anyway. Sometimes this magically fixes things.
If that didn't help; in Safari you might want to "Reset Safari" and/or "Empty Cache." Be sure to read the caveats before clicking on the final "reset" and "empty" buttons to make sure you understand the ramifications....one of which might require re-installing Safari Enhancer (for example).
Glad to hear Opera did the trick on FOCUS.
-JB