Major airline hiring departments are well aware of that. Its always something that is better to have than not to have, but they generally all know the places and the timing when its just not possible. If they don't and they ask, tell them you did everything you could but the opportunity wasn't there at the time.

Intentionally bypassing to be senior in the right seat when you've never had any PIC time however…

That one is much harder to explain when your resume is already marginal.