Regional airlines are pretty much all the same. It's like two homeless people arguing who's box is better than the other.
It's ultimately your choice, weigh the pros and cons to each regional, see who's hiring and who's not. Are you going to wait for skywest to hire because they are the "better" regional (currently not hiring) or are you going for american eagle who is hiring, but their upgrade times are high.

Good luck with your choice.