Small detail but is a big help in commuter QOL.... Leave your roll aboard in base and just commute with a small duffel with laundry and iPad. It is a lot less stressful to not drag your whole life with you.
I also carry a small inflatable pillow and assorted comfort stuff like gum, phone charger, ear plugs, wipes, keys, etc. in a small bag that I can put in the seat pocket: that way if I get a middle seat I have everything I want.